David Guo 郭政睿

David Guo 郭政睿

PhD Student

Hong Kong University of Science and Technology

Research Interests

Computational Pathology
Foundation Models
Vision-Language Large Models

About

I am a PhD student at the SMART Lab, Department of Computer Science and Engineering, Hong Kong University of Science and Technology, advised by Prof. Hao Chen. Prior to this, I obtained my BSc degree in Applied Mathematics from Harbin Institute of Technology (Weihai).

My current research focuses on developing powerful vision and vision-language foundation models for computational pathology. In the meantime, I'm actively collaborating with clinicians and pathologists to integrate our model into real-world diagnostic workflow.

Selected Publications

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A generalizable pathology foundation model using a unified knowledge distillation pretraining framework

Jiabo Ma, Zhengrui Guo, Fengtao Zhou, Yihui Wang, Yingxue Xu, Jinbang Li, Fang Yan, Yu Cai, Zhengjie Zhu, Cheng Jin, Yi Lin, Xinrui Jiang, Chenglong Zhao, Danyi Li, Anjia Han, Zhenhui Li, Ronald Cheong Kin Chan, Jiguang Wang, Peng Fei, Kwang-Ting Cheng, Shaoting Zhang, Li Liang, Hao Chen.

Nature Biomedical Engineering

FOCUS: Knowledge-enhanced adaptive visual compression for few-shot whole slide image classification

Zhengrui Guo, Conghao Xiong, Jiabo Ma, Qichen Sun, Lishuang Feng, Jinzhuo Wang, Hao Chen

CVPR 2025

LLM-driven medical report generation via communication-efficient heterogeneous federated learning

Haoxuan Che, Haibo Jin, Zhengrui Guo, Yi Lin, Cheng Jin, Hao Chen

IEEE Transactions on Medical Imaging

BLEND: Behavior-guided Neural Population Dynamics Modeling via Privileged Knowledge Distillation

Zhengrui Guo, Fangxu Zhou, Wei Wu, Qichen Sun, Lishuang Feng, Jinzhuo Wang, Hao Chen

ICLR 2025

Context matters: Query-aware dynamic long sequence modeling of gigapixel images

Zhengrui Guo, Qichen Sun, Jiabo Ma, Lishuang Feng, Jinzhuo Wang, Hao Chen

ICML 2025

HistGen: Histopathology report generation via local-global feature encoding and cross-modal context interaction

Zhengrui Guo, Jiabo Ma, Yingxue Xu, Yihui Wang, Liansheng Wang, Hao Chen

MICCAI 2024

News

2026-01

Our work Manifold Residual (MR) Block for Few-shot WSI classification has been accepted by ICLR 2026, Congrats to Conghao 🎉 Check paper here.

2025-09

Our generalizable pathology foundation model GPFM has been published on Nature Biomedical Engineering 🎉 Check paper here.

2025-07

Our work FedMRG has been accepted by TMI 🎉 Check paper here.

2025-05

Our work Querent has been accepted by ICML 2025 🎉 Check paper here.

2025-02

Our work FOCUS has been accepted by CVPR 2025 🎉 Check paper here.

2025-01

Another paper (NeurPIR) has been accepted by ICLR 2025, Congrats to WU Wei 🎉 Check paper here.

2025-01

Our work BLEND has been accepted by ICLR 2025 🎉 Check paper here.

2024-07

I passed the PhD Qualification Exam of HKUST!

2024-06

Our work HistGen has been accepted by MICCAI 2024 🎉 Check paper here.